DISEASE & VACCINATION

29 indicators · 1900–2026 · every value from its primary publisher

┊ dashed lines mark 1979 Oil shock & inflation peak · 1987 Black Monday crash · 1991 Gulf War recession · 2001 Dot-com bust & 9/11 · 2008 Global financial crisis · 2020 COVID-19 pandemic

50 Years Since 2000 10 Years 5 Years 1 Year

Measles (rubeola)reported cases per 100,000 population · 1980–2026 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

0.912026 thru Sep

−85% since 1980
5.96 then

Pertussis (whooping cough)reported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

2.092023

+175% since 1980
0.76 then

Tuberculosisreported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

2.862023

−77% since 1980
12.25 then

Lyme diseasereported cases per 100,000 population · 2008–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

26.542023

+127% since 2008
11.67 then

Syphilis, Primary and secondaryreported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

15.722023

+31% since 1980
12.00 then

Congenital syphilisreported cases · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

3,8822023

+1301% since 1980
277 then

Gonorrheareported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

178.32023

−60% since 1980
442.1 then

Chlamydiareported cases per 100,000 population · 1985–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

488.92023

+2707% since 1985
17.42 then

Acute hepatitis A viral infectionreported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

0.492023

−96% since 1980
12.84 then

Acute hepatitis B viral infectionreported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

0.662023

−92% since 1980
8.39 then

Acute hepatitis C viral infectionreported cases per 100,000 population · 1990–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

1.642023

+59% since 1990
1.03 then

Mumpsreported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

0.132023

−97% since 1980
3.86 then

Meningococcal diseasereported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

0.132023

−90% since 1980
1.25 then

Haemophilus influenzae, invasive disease, all serotypes, all agesreported cases per 100,000 population · 1991–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

2.022023

+84% since 1991
1.10 then

Salmonellosis (excluding Salmonella Typhi and Salmonella Paratyphi infections)reported cases per 100,000 population · 1980–2023 · NCHS Health, United States (Table IDNotif) · CDC NNDSS annual summary via WONDER

18.072023

+21% since 1980
14.88 then

Influenza and pneumoniaage-adjusted deaths per 100,000 population (2000 U.S. standard population) · 1976–2024 · NCHS Health, United States (Table SlctMort) · CDC WONDER Underlying Cause of Death (final)

11.22024

−71% since 1976
38.8 then

Human immunodeficiency virus (HIV) diseaseage-adjusted deaths per 100,000 population (2000 U.S. standard population) · 1987–2024 · NCHS Health, United States (Table SlctMort) · CDC WONDER Underlying Cause of Death (final)

1.22024

−79% since 1987
5.6 then

COVID-19 deathsdeaths · 2020–2026 · National Center for Health Statistics, Provisional COVID-19 Death Counts by Week Ending Date and State

6,1782026

−98% since 2020
367,923 then

MMR ≥1 dose by 24 monthspercent · 2011–2022 · CDC NIS-Child (ChildVaxView), National Immunization Survey

91.4%2022

+1.3 pts since 2011
90.1% then

DTaP ≥4 doses by 24 monthspercent · 2011–2022 · CDC NIS-Child (ChildVaxView), National Immunization Survey

80.9%2022

+0.2 pts since 2011
80.7% then

Combined 7-vaccine series by 24 monthspercent · 2011–2022 · CDC NIS-Child (ChildVaxView), National Immunization Survey

69.0%2022

+1.3 pts since 2011
67.7% then

MMR coverage among kindergartners, nationalpercent · 2010–2026 · CDC School Vaccination Assessment (SchoolVaxView)

92.4%2026

−2.0 pts since 2010
94.4% then

Kindergartners with any vaccination exemptionpercent · 2010–2026 · CDC School Vaccination Assessment (SchoolVaxView)

4.2%2026

+2.5 pts since 2010
1.7% then

Kindergartners with a non-medical vaccination exemptionpercent · 2010–2026 · CDC School Vaccination Assessment (SchoolVaxView)

4.0%2026

+2.5 pts since 2010
1.5% then

Tdap ≥1 dose, ages 13–17 yearspercent · 2006–2025 · CDC NIS-Teen (TeenVaxView), National Immunization Survey

88.8%2025

+78 pts since 2006
10.8% then

HPV ≥1 dose, females aged 13–17 yearspercent · 2006–2025 · CDC NIS-Teen (TeenVaxView), National Immunization Survey

78.7%2025

+78 pts since 2006
1.0% then

Seasonal influenza vaccination, ≥6 months, nationalpercent · 2011–2025 · CDC FluVaxView

43.8%2025

+0.8 pts since 2011
43.0% then

Seasonal influenza vaccination, ≥65 years, FluVaxViewpercent · 2011–2025 · CDC FluVaxView

63.8%2025

−2.8 pts since 2011
66.6% then

Pneumococcal vaccination, ≥65 years, CDC adult coveragepercent · 2008–2024 · CDC adult vaccination coverage

70.3%2024

+4.5 pts since 2008
65.8% then

Data

Complete year-by-year values, raw numbers in the unit in each column header. Machine-readable: stats.json · stats.csv.

Year	Measles (rubeola)reported cases per 100,000 population · 1950–2026 (2026 thru Sep)	Pertussis (whooping cough)reported cases per 100,000 population · 1950–2023	Tuberculosisreported cases per 100,000 population · 1960–2023	Lyme diseasereported cases per 100,000 population · 2008–2023	Syphilis, Primary and secondaryreported cases per 100,000 population · 1950–2023	Congenital syphilisreported cases · 1950–2023	Gonorrheareported cases per 100,000 population · 1950–2023	Chlamydiareported cases per 100,000 population · 1985–2023	Acute hepatitis A viral infectionreported cases per 100,000 population · 1970–2023	Acute hepatitis B viral infectionreported cases per 100,000 population · 1970–2023	Acute hepatitis C viral infectionreported cases per 100,000 population · 1990–2023	Mumpsreported cases per 100,000 population · 1970–2023	Meningococcal diseasereported cases per 100,000 population · 1970–2023	Haemophilus influenzae, invasive disease, all serotypes, all agesreported cases per 100,000 population · 1991–2023	Salmonellosis (excluding Salmonella Typhi and Salmonella Paratyphi infections)reported cases per 100,000 population · 1960–2023	Influenza and pneumoniaage-adjusted deaths per 100,000 population (2000 U.S. standard population) · 1900–2024	Human immunodeficiency virus (HIV) diseaseage-adjusted deaths per 100,000 population (2000 U.S. standard population) · 1987–2024	COVID-19 deathsdeaths · 2020–2026	MMR ≥1 dose by 24 monthspercent · 2011–2022	MMR ≥1 dose, children 19–35 monthspercent · 1995–2017	DTaP ≥4 doses by 24 monthspercent · 2011–2022	DTaP ≥4 doses, children 19–35 monthspercent · 1995–2017	Combined 7-vaccine series by 24 monthspercent · 2011–2022	Combined 7-vaccine series, children 19–35 monthspercent · 2009–2017	MMR coverage among kindergartners, nationalpercent · 2010–2026	Kindergartners with any vaccination exemptionpercent · 2010–2026	Kindergartners with a non-medical vaccination exemptionpercent · 2010–2026	Tdap ≥1 dose, ages 13–17 yearspercent · 2006–2025	HPV ≥1 dose, females aged 13–17 yearspercent · 2006–2025	HPV up-to-date, males and females aged 13–17 yearspercent · 2016–2025	Seasonal influenza vaccination, ≥6 months, nationalpercent · 2011–2025	Seasonal influenza vaccination, ≥65 years, FluVaxViewpercent · 2011–2025	Seasonal influenza vaccination, ≥65 years, NHISpercent · 1989–2016	Pneumococcal vaccination, ≥65 years, CDC adult coveragepercent · 2008–2024	Pneumococcal vaccination, ever received, ≥65 years, NHISpercent · 1989–2016
1900																297.5
1901																312.9
1902																219.3
1903																251.1
1904																291.2
1905																257.8
1906																222.5
1907																285.4
1908																234.6
1909																221.2
1910																238.4
1911																234.1
1912																213.7
1913																214.8
1914																202.4
1915																238.1
1916																278.5
1917																267
1918																612.4
1919																270.9
1920																279.2
1921																153.1
1922																207.6
1923																253
1924																182
1925																198.1
1926																233
1927																164
1928																236.4
1929																247.5
1930																159.8
1931																170.2
1932																180
1933																156.5
1934																152.9
1935																163.8
1936																186.7
1937																181.8
1938																124.3
1939																124.4
1940																117.6
1941																104.6
1942																84.7
1943																101.7
1944																94.7
1945																74.9
1946																69.9
1947																65.9
1948																58
1949																45.1
1950	211.01	79.82			16.73	13377	192.5									48.1
1951																47.4
1952																43.1
1953																49.2
1954																36.2
1955																39.2
1956																40.8
1957																50.3
1958																47.4
1959																44.3
1960	245.42	8.23	30.83		9.06	4416	145.4								3.85	53.7
1961																43.4
1962																47.1
1963																55.6
1964																45.4
1965																46.8
1966																47.9
1967																42.2
1968																52.8
1969																47.9
1970	23.23	2.08	18.28		10.8	1953	294.2		27.87	4.08		55.55	1.23		10.84	41.7
1971																38.4
1972																41.3
1973																41.2
1974																35.5
1975																34.9
1976																38.8
1977																31
1978																34.5
1979																26.1
1980	5.96	0.76	12.25		12	277	442.1		12.84	8.39		3.86	1.25		14.88	31.4
1981																30
1982																26.5
1983																29.8
1984																30.6
1985	1.18	1.5	9.3		11.4	329	382.98	17.42	10.03	11.5		1.3	1.04		27.37	34.5
1986																34.8
1987																33.8	5.6
1988	1.38	1.4	9.13		16.55	741	301.86	87.13	11.6	9.43		2.05	1.21		19.91	37.3	6.9
1989	7.33	1.67	9.46		18.57	1837	297.09	102.45	14.43	9.43		2.34	1.1		19.26	35.9	9																30.4		14.1
1990	11.17	1.84	10.33		20.26	3865	276.43	160.19	12.64	8.48	1.03	2.17	0.99		19.54	36.8	10.2
1991	3.82	1.08	10.42		16.98	4424	245.84	179.66	9.67	7.14	1.42	1.72	0.84	1.1	19.1	34.9	11.7																41.7		21.2
1992	0.88	1.6	10.46		13.26	4067	196.04	182.35	9.06	6.32	2.36	1.03	0.84	0.55	16.04	33.1	13.1
1993	0.12	2.55	9.82		10.21	3420	171.07	178.05	9.4	5.18	1.86	0.66	1.02	0.55	16.15	35.2	14.4																52		28.2
1994	0.37	1.77	9.36		7.84	2452	163.93	192.49	10.29	4.81	1.78	0.6	1.11	0.45	16.64	33.9	16																55.3		29.7
1995	0.12	1.97	8.7		6.21	1863	147.46	187.84	12.13	4.19	1.78	0.35	1.25	0.45	17.66	33.8	16.2			90		78											58.2		34
1996	0.2	2.94	8.04		4.23	1282	121.82	190.57	11.7	4.01	1.41	0.29	1.3	0.45	17.15	33.2	11.5			91		81
1997	0.06	2.46	7.42		3.14	1082	120.18	205.49	11.22	3.9	1.43	0.27	1.24	0.44	15.66	33.6	6			90		82											63.2		42.4
1998	0.04	2.74	6.79		2.54	843	129.23	231.83	8.59	3.8	1.3	0.25	1.01	0.44	16.17	34.6	4.9			92		83.9											63.3		46
1999	0.04	2.67	6.43		2.37	580	129.31	247.16	6.25	2.82	1.14	0.14	0.92	0.48	14.89	23.5	5.3			91.5		83.3											65.7		49.7
2000	0.03	2.88	6.01		2.12	580	128.67	251.38	4.91	2.95	1.17	0.13	0.83	0.51	14.51	23.7	5.2			90.5		81.7											64.4		53.1
2001	0.04	2.69	5.68		2.14	506	126.77	274.52	3.77	2.79	1.41	0.1	0.83	0.57	14.39	22.2	5			91.4		82.1											63.1		54
2002	0.02	3.47	5.36		2.38	460	122.01	289.41	3.13	2.84	0.65	0.1	0.64	0.62	15.73	23.2	4.9			91.6		81.6											65.7		56
2003	0.02	4.04	5.17		2.47	432	115.23	301.74	2.66	2.61	0.38	0.08	0.61	0.7	15.16	22.6	4.7			93		84.8											65.5		55.6
2004	0.01	8.88	5.09		2.72	375	112.42	316.51	1.95	2.14	0.31	0.09	0.47	0.72	14.47	20.4	4.5			93		85.5											64.6		56.8
2005	0.02	8.72	4.8		2.94	339	114.57	329.42	1.53	1.78	0.23	0.11	0.42	0.78	15.43	21	4.2			91.5		85.7											59.7		56.2
2006	0.02	5.27	4.65		3.26	372	119.7	344.33	1.21	1.62	0.26	2.22	0.4	0.82	15.45	18.4	4			92.3		85.2						10.8	1				64.3		57.1
2007	0.01	3.49	4.44		3.8	435	118.03	367.47	1	1.51	0.28	0.27	0.36	0.85	16.03	16.8	3.7			92.3		84.5						30.4	25.1				66.7		57.7
2008	0.05	4.4	4.28	11.67	4.44	446	110.75	398.12	0.86	1.34	0.29	0.15	0.39	0.96	16.92	17.6	3.3			92.1		84.6						40.8	37.2				67.2	65.8	60
2009	0.02	5.54	3.8	12.71	4.56	431	98.1	405.26	0.65	1.12	0.27	0.65	0.32	0.99	16.18	16.5	3			90		83.9		44.3				55.6	44.3				66.8	66.7	60.6
2010	0.02	8.97	3.64	9.86	4.46	387	100.19	423.62	0.54	1.1	0.29	0.85	0.27	1.03	17.73	15.1	2.6			91.5		84.4		56.6	94.4	1.7	1.5	68.7	48.7				63.9	68	59.7
2011	0.06	6.06	3.41	10.78	4.48	358	103.29	453.41	0.45	0.94	0.42	0.13	0.25	1.15	16.79	15.7	2.4		90.1	91.6	80.7	84.6	67.7	68.5				78.2	53		43	66.6	66.9	69.6	62.3
2012	0.02	15.49	3.19	9.96	4.99	334	106.66	453.3	0.5	0.93	0.59	0.07	0.18	1.1	17.27	14.4	2.2		90.6	90.8	81.4	82.5	69	68.4	94.7	1.6	1.4	84.6	53.8		41.8	64.9	66.5	68.3	59.9
2013	0.06	9.12	3.05	11.62	5.5	362	105.34	443.46	0.57	0.97	0.71	0.19	0.18	1.21	16.13	15.9	2.1		90.3	91.9	81.2	83.1	68.3	70.4	94.1	1.9	1.7	86	57.3		45	66.2	67.9	68.4	59.7
2014	0.21	10.34	2.95	10.54	6.27	462	109.79	452.17	0.39	0.88	0.73	0.38	0.14	1.11	16.14	15.1	2		89.8	91.5	80.1	84.2	68.5	71.6	94	2.1	2	87.6	60		46.2	65	70.1	69.3	61.3
2015	0.06	6.46	2.97	11.9	7.43	494	122.96	474.97	0.43	1.06	0.81	0.41	0.12	1.29	17.15	15.2	1.9		90.8	91.9	80.7	84.6	68.3	72.2	94	2.2	2	86.4	62.8		47.1	66.7	69.1	71.9	63.6
2016	0.03	5.56	2.87	11.32	8.61	641	144.99	494.65	0.62	1	0.97	1.97	0.12	1.51	16.67	13.5	1.8		90.8	91.1	80.4	83.4	69.7	70.7	94.7	2.1	1.9	88	65.1	43.4	45.6	63.4	67.5	72.4	66.9
2017	0.04	5.83	2.8	13.18	9.41	941	170.58	524.55	1.03	1.05	1.36	1.88	0.11	1.7	16.67	14.3	1.6		90.4	91.5	80.9	83.2	69.8	70.4	95	2.1	1.8	88.7	68.6	48.6	46.8	65.3		74.7
2018	0.11	4.77	2.76	10.34	10.72	1323	178.32	537.54	3.81	1.02	1.54	0.77	0.1	1.7	18.64	14.9	1.5		92.3		82.3		70.1		95	2.3	1.9	88.9	69.9	51.1	41.7	59.6		71.8
2019	0.39	5.67	2.72	10.69	11.92	1870	188.4	552.84	5.74	1.09	1.74	1.15	0.11	1.87	17.78	12.3	1.4		91.5		81.3		70.1		94.7	2.5	2.2	90.2	73.2	54.2	49.2	68.1		71.7
2020	0	1.85	2.16	5.42	12.55	2148	204.23	476.05	3	0.65	1.82	0.21	0.07	0.9	13.69	13	1.4	367923	90.2		79.6		68		95.2	2.5	2.2	90.1	77.1	58.6	51.8	69.8		70.3
2021	0.01	0.64	2.37	7.4	15.95	2820	210.43	485.43	1.72	0.61	1.81	0.06	0.06	0.92	14.81	10.5	1.3	471027	90.2		80.4		67		93.9	2.2	1.9	89.6	78.5	61.7	52.1	75.2		70.1
2022	0.04	0.91	2.49	18.67	17.65	3755	193.8	493.34	0.68	0.64	1.68	0.12	0.09	1.6	16.79	11.3	1.3	256290	91.4		80.9		69		93	2.6	2.3	89.9	77.8	62.6	51.4	73.9		70
2023	0.02	2.09	2.86	26.54	15.72	3882	178.34	488.94	0.49	0.66	1.64	0.13	0.13	2.02	18.07	10.9	1.3	75725							93.1	3	2.8	89	78.5	61.4	49.3	69.7		70.2
2024	0.08															11.2	1.2	47494							92.7	3.3	3.1	91.3	79.1	62.9	47.2	69.7		70.3
2025	0.67																	20840							92.5	3.6	3.4	88.8	78.7	63.4	43.8	63.8
2026	0.91																	6178							92.4	4.2	4

Sources